A review of malaria vaccine clinical projects based on the WHO rainbow table (Publications)
Development and Phase 3 testing of the most advanced malaria vaccine, RTS,S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of several research malaria vaccines have
<em>Trypanosoma brucei gambiense</em> group 1 is distinguished by a unique amino acid substitution in the HpHb receptor implicated in human serum... (Publications)
Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the ac
Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance (Publications)
BACKGROUND: Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment. In 2007, the majority of worldwi
<em>Dipetalonema viteae</em> (Filarioidea): development of the infective larvae in vitro (Publications)
The development of Dipetalonema viteae third stage larvae was attempted in vitro. A monophasic culture system consisting of BHK-21 medium supplemented with 10% tryptose-phosphate broth and 15% fresh j
Design and pre-clinical profiling of a <em>Plasmodium falciparum</em> MSP-3 derived component for a multi-valent virosomal malaria vaccine (Publications)
BACKGROUND: Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion i
Studies on the mechanisms supporting the continuous growth of <em>Trypanosoma (Trypanozoon) brucei</em> as bloodstream-like form in vitro (Publications)
The conditions which enable growth of Trypanosoma (T.) brucei stock S 427 as bloodstream-like form over bovine fibroblast-like cells (BHF) were analyzed. The experiments with different BHF conditioned
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug... (Publications)
BACKGROUND: A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider imple
Validation of activity questionnaires in patients with cystic fibrosis by accelerometry and cycle ergometry (Publications)
BACKGROUND: The objective of this study was to validate physical activity questionnaires for cystic fibrosis (CF) against accelerometry and cycle ergometry. METHODS: 41 patients with CF (12-42 years)