Individual responses to a single oral dose of albendazole indicate reduced efficacy against soil-transmitted helminths in an area with high drug... (Publications)
BACKGROUND: Albendazole (ALB) is administered annually to millions of children through global deworming programs targeting soil-transmitted helminths (STHs: Ascaris lumbricoides, Trichuris trichiura a
Unlocking the human factor to increase effectiveness and sustainability of malaria vector control (Publications)
BACKGROUND: Progress in the fight against malaria has stalled in recent years, highlighting the importance of new interventions and tailored approaches. A critical factor that must be considered acros
Investigating the association between long-term exposure to air pollution and greenness with mortality from neurological, cardio-metabolic and chronic... (Publications)
Long-term exposure to air pollution has been associated with increased natural-cause mortality, but the evidence on diagnoses-specific mortality outcomes is limited. Few studies have examined the pote
Health of farming communities prior to modification of the occupational environment through a watershed development project in Kolar, India (Publications)
Background: Watershed development (WSD) projects, aimed primarily at enhancing soil and water conservation and supporting livelihoods in semi‑arid areas, have the potential to impact health by modifyi
What does a pandemic proof health system look like? (Publications)
Switzerland is currently in a lockdown and other lockdowns are looming world-wide. Many countries in the West are now experiencing a third COVID-19 wave. While some scientists are aiming for Zero Covi
<em>In vitro, in vivo</em>, and ADME evaluation of SF5-containing <em>N,N'</em>-diarylureas as antischistosomal agents (Publications)
In recent years, N,N'-diarylureas have emerged as a promising chemotype for the treatment of schistosomiasis, a disease that poses a considerable health burden to millions of people worldwide. Here, w
Prevalence of SARS-CoV-2 in household members and other close contacts of COVID-19 cases: a serologic study in canton of Vaud, Switzerland (Publications)
BACKGROUND: Research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission within households and other close settings using serological testing is scarce. METHODS: We invited co
Control and elimination of schistosomiasis as a public health problem: thresholds fail to differentiate schistosomiasis morbidity prevalence in... (Publications)
BACKGROUND: Current World Health Organization guidelines utilize prevalence of heavy-intensity infections (PHIs), that is, ≥50 eggs per 10 mL of urine for Schistosoma haematobium and ≥400 eggs per gra
A mechanistic and data-driven reconstruction of the time-varying reproduction number: application to the COVID-19 epidemic (Publications)
The effective reproduction number Reff is a critical epidemiological parameter that characterizes the transmissibility of a pathogen. However, this parameter is difficult to estimate in the presence o
Building a multisystemic understanding of societal resilience to the COVID-19 pandemic (Publications)
The current global systemic crisis reveals how globalised societies are unprepared to face a pandemic. Beyond the dramatic loss of human life, the COVID-19 pandemic has triggered widespread disturbanc