Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: beyond mortality from cardiopulmonary disease... (Publications)
BACKGROUND: The association between long-term exposure to air pollution and mortality from cardiorespiratory diseases is well established, yet the evidence for other diseases remains limited. OBJECTIV
<em>In vitro</em> antischistosomal activity of <em>Artemisia annua</em> and <em>Artemisia afra</em> extracts (Publications)
Background Schistosomiasis, a neglected tropical disease, imposes substantial health and economic burdens on impoverished groups living in predominantly rural areas. Praziquantel (PZQ) is the only dru
Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): study... (Publications)
INTRODUCTION: To sustainably provide good quality care to increasing numbers of people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in resource-limited settings, care delivery must s
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy (Publications)
Aminoacyl transfer RNA (tRNA) synthetases (aaRSs) are attractive drug targets, and we present class I and II aaRSs as previously unrecognized targets for adenosine 5'-monophosphate-mimicking nucleosid
Assessment of FDA-approved drugs against <em>Strongyloides ratti in vitro</em> and <em>in vivo</em> to identify potentially active drugs against... (Publications)
BACKGROUND: Infections with Strongyloides stercoralis belong to the most neglected helminth diseases, and research and development (R&D) efforts on novel drugs are inadequate. METHODS: A commercially
Impact of vaccination and non-pharmaceutical interventions on SARS-CoV-2 dynamics in Switzerland (Publications)
BACKGROUND: As vaccination coverage against SARS-CoV-2 increases amidst the emergence and spread of more infectious and potentially more deadly viral variants, decisions on timing and extent of relaxi
Soil-transmitted helminth infections and nutritional indices among Filipino schoolchildren (Publications)
BACKGROUND: Soil-transmitted helminth (STH) infections are still prevalent among schoolchildren in the Philippines. We evaluated the risk factors associated with STH and the relationship between STH a
Methodological approaches for conducting follow-up research with clinical trial participants: a scoping review and expert interviews (Publications)
BACKGROUND: Evidence-based establishment and implementation of best principles, laws and ordinances that regulate clinical research depend on the consultation and involvement of trial participants. Ye
Incidence and consequences of damage to insecticide-treated mosquito nets in Kenya (Publications)
BACKGROUND: Efforts to improve the impact of long-lasting insecticidal nets (LLINs) should be informed by understanding of the causes of decay in effect. Holes in LLINs have been estimated to account