New derivatives of the multi-stage active Malaria Box compound MMV030666 and their antiplasmodial potencies (Publications)
MMV’s Malaria Box compound MMV030666 shows multi-stage activity against various strains of Plasmodium falciparum and lacks resistance development. To evaluate the importance of its diarylether partial
"It's the poverty": stakeholder perspectives on barriers to secondary education in rural Burkina Faso (Publications)
Universal primary and secondary education is a key target of the Sustainable Development Goals. While substantial gains have been made at the primary school level, progress towards universal secondary
Evaluation of the diagnostic performance of PanbioTM Abbott SARS-CoV-2 rapid antigen test for the detection of COVID-19 from suspects attending ALERT... (Publications)
BACKGROUND: The emergence and rapid spread of coronavirus disease 2019 (COVID-19), a potentially lethal disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is causing publi
Efficacy and safety of acoziborole in patients with human African trypanosomiasis caused by <em>Trypanosoma brucei gambiense</em>: a multicentre,... (Publications)
Summary Background Human African trypanosomiasis caused by Trypanosoma brucei gambiense (gambiense HAT) in patients with late-stage disease requires hospital admission to receive nifurtimox–eflornithi
Efficacy and safety of moxidectin and albendazole compared with ivermectin and albendazole coadministration in adolescents infected with <em>Trichuris... (Publications)
BACKGROUND: Control efforts against soil-transmitted helminths focus on preventive chemotherapy with albendazole and mebendazole, however these drugs yield unsatisfactory results against Trichuris tri
Genetically modified malaria parasites as vaccine candidates (Publications)
Induction of sterile immunity against sporozoite and liver stages of malaria is a long-standing aim in vaccine development. Genetically engineered, attenuated sporozoites were systematically evaluated
A comparison of statistical and machine-learning approaches for spatiotemporal modeling of nitrogen dioxide across Switzerland (Publications)
Land use regression modeling has commonly been used to model ambient air pollutant concentrations in environmental epidemiological studies. Recently, other statistical and machine-learning methods hav
Stigma-directed services (Stig2Health) to improve 'linkage to care' for people living with HIV in rural Tanzania: study protocol for a nested pre-post... (Publications)
Background: HIV-related stigma is a major barrier to the timely linkage and retention of patients in HIV care in sub-Saharan Africa, where most people living with HIV/AIDS reside. In this implementati
Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease (Publications)
RATIONALE: Eosinophils are associated with airway inflammation in respiratory disease. Eosinophil production and survival is controlled partly by interleukin-5: anti-interleukin-5 agents reduce asthma