Bicyclo[2.2.2]octyl esters of dialkylamino acids as antiprotozoals (Publications)
A couple of bicyclo[2.2.2]octyl esters of 2-dialkylaminoacetic acids were prepared. Their antiplasmodial and antitrypanosomal activities against Trypanosoma brucei rhodesiense (STIB 900) and the K(1)
Differential gene expression in LPS/IFNgamma activated microglia and macrophages: in vitro versus in vivo (Publications)
Two different macrophage populations contribute to CNS neuroinflammation: CNS-resident microglia and CNS-infiltrating peripheral macrophages. Markers distinguishing these two populations in tissue sec
A trichinellosis outbreak in Borikhamxay Province, Lao PDR (Publications)
Trichinellosis is documented in Southeast Asia, particularly in Thailand and China. Data from Lao PDR are lacking. An outbreak investigation was conducted in Borikhamxay Province after three patients
Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl omega-aminoalkanoates (Publications)
Several 4-aminobicyclo[2.2.2]octyl esters of omega-dialkylamino acids were prepared. Their activities against the multidrug-resistant K(1) strain of Plasmodium falciparum and Trypanosoma brucei rhodes
Perceived ill-health and health seeking behavior in two communities in the nam theun 2 hydroelectric project area in Lao People's Democratic... (Publications)
Objective :To compare perceived ill-health and health seeking behavior between two communities affected by the large Nam Theun 2 hydroelectric project in central Lao People's Democratic Republic (PDR)
Spiroindolones, a potent compound class for the treatment of malaria (Publications)
Recent reports of increased tolerance to artemisinin derivatives--the most recently adopted class of antimalarials--have prompted a need for new treatments. The spirotetrahydro-beta-carbolines, or spi
Modelling the geographical distribution of co-infection risk from single-disease surveys (Publications)
Background: The need to deliver interventions targeting multiple diseases in a cost-effective manner calls for integrated disease control efforts. Consequently, maps are required that show where the r
Neglected diseases and ethnic minorities in the Western Pacific Region: exploring the links (Publications)
Ethnic minority groups (EMGs) are often subject to exclusion, marginalization and poverty. These characteristics render them particularly vulnerable to neglected diseases, a diverse group of diseases