Structure elucidation and activity of kolossin A, the D-/L-pentadecapeptide product of a giant nonribosomal peptide synthetase (Publications)
The largest continuous bacterial nonribosomal peptide synthetase discovered so far is described. It consists of 15 consecutive modules arising from an uninterrupted, fully functional gene in the entom
Molecular and culture-based diagnosis of <em>Clostridium difficile</em> isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain... (Publications)
BACKGROUND: Although Clostridium difficile is a major cause of diarrhoea, its epidemiology in tropical settings is poorly understood. Strain characterisation requires work-up in specialised laboratori
Preparation of antimalarial endoperoxides by a formal [2 + 2 + 2] cycloaddition (Publications)
A formal [2 + 2 + 2] cycloaddition reaction between a 1,3-dione, an olefin, and molecular oxygen mediated by light is reported, which delivers endoperoxides in good yield through the formation of two
Do existing research summaries on health systems match immunisation managers' needs in middle- and low-income countries? Analysis of GAVI health... (Publications)
ABSTRACT: BACKGROUND: The GAVI Alliance was created in 2000 to increase access to vaccines. More recently, GAVI has supported evidence-based health systems strengthening to overcome barriers to vaccin
Artesunate-mefloquine combination therapy in acute <em>Plasmodium falciparum</em> malaria in young children: a field study regarding neurological and... (Publications)
BACKGROUND: Mefloquine-artesunate combination therapy for uncomplicated falciparum malaria is one of the treatments used in African children. Data concerning neurological safety in adults and children
High prevalence of bovine tuberculosis in dairy cattle in central Ethiopia: implications for the dairy industry and public health (Publications)
BACKGROUND: Ethiopia has the largest cattle population in Africa. The vast majority of the national herd is of indigenous zebu cattle maintained in rural areas under extensive husbandry systems. Howev
Gender differences in disordered eating and weight dissatisfaction in Swiss adults: which factors matter? (Publications)
BACKGROUND: Research results from large, national population-based studies investigating gender differences in weight dissatisfaction and disordered eating across the adult life span are still limited
An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells (Publications)
ABSTRACT: BACKGROUND: The generation of monoclonal antibodies specific for protein antigens usually depends on purified recombinant protein for both immunisation and hybridoma screening. Purification