Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in... (Publications)
OBJECTIVES: WHO guidelines on ART define the HIV-1 viral load (VL) threshold for treatment failure at 1000 copies/mL. The Switch Either near Suppression Or THOusand (SESOTHO) trial, conducted in Lesot
Hitzebedingte Sterblichkeit im Sommer 2019 (Publications)
Der Sommer 2019 gilt als drittheissester Sommer seit Messbeginn in der Schweiz. Zwei intensive Hitzewellen mit einer mittleren Maximaltemperatur von 32–34°C prägten die Monate Juni und Juli 2019. Inwi
Phylogenomics of <em>Mycobacterium africanum</em> reveals a new lineage and a complex evolutionary history (Publications)
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis sensu stricto, as well as two
Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a... (Publications)
Background: Infections with soil-transmitted helminths (STHs) may result in chronic inflammatory disorders affecting the human host. The objective of this study was to evaluate Fecal Calprotectin (FC)
New methodological approaches to monitor long lasting insecticidal nets (LLINs) durability for sustained malaria control (Publications)
Long lasting insecticidal nets (LLINs) are the current primary vector control measure to prevent malaria transmission. They function by inhibiting mosquitoes from blood feeding and also killing mosqui
Mining Sudanese medicinal plants for natural compounds against malaria and neglected tropical diseases (Publications)
Tropical parasitic diseases such as malaria, human African trypanosomiasis, Chagas disease, mycetoma, and leishmaniasis affect more than a billion people worldwide and have devastating consequences. T
<em>myo</em>-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in <em>Trypanosoma brucei</em> (Publications)
myo-Inositol is an essential precursor for the production of inositol phosphates and inositol phospholipids in all eukaryotes. Intracellular myo-inositol is generated by de novo synthesis from glucose