Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population [Short communication] (Publications)
Lipoarabinomannan (LAM), a cell wall component of mycobacteria, can be detected in the urine of tuberculosis (TB) patients. Advantages of this diagnostic include the ease of sample collection and test
Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)
In studies with predominately male patients, B-type natriuretic peptide (BNP) levels have been shown to be helpful in the evaluation and management of patients who present with acute dyspnea. The effe
The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) (Publications)
Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through 'preventive chemotherapy' programmes to school-aged children or at-risk populations.
Association between sleep disturbances and falls among the elderly: results from the German cooperative health research in the region of Augsburg-age... (Publications)
OBJECTIVE: We aimed to examine the association between various sleep disturbances and falls among older individuals from the general population while considering the influence of age and dizziness. ME
A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep (Publications)
Caffeine is the most widely used stimulant in Western countries. Some people voluntarily reduce caffeine consumption because it impairs the quality of their sleep. Studies in mice revealed that the di
Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: <em>in vivo</em> studies (Publications)
Background: Chagas disease is caused by the parasite Trypanosoma cruzi, is endemic in Latin America and leads to an estimated 14,000 deaths per year and around 100 million people at risk of infection.
In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine (Publications)
CONTEXT: The emergence and spread of Plasmodium falciparum-resistant parasites to nearly all available antimalarial drugs pose a threat to malaria control and necessitates the need to continue the sea
Oxantel pamoate-albendazole for <em>Trichuris trichiura</em> infection (Publications)
BACKGROUND: Infections with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) are widespread and often occur concomitantly. These parasitic-worm infections are typic
Antiparasitic chaiyaphumines from entomopathogenic <em>Xenorhabdus</em> sp. PB61.4 (Publications)
A new class of four depsipentapeptides called chaiyaphumines A-D (1-4) was isolated from Xenorhabdus sp. PB61.4. Their structures were elucidated by detailed 1D and 2D NMR experiments and by a Marfey'