Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in <em>Plasmodium falciparum</em> (Publications)
Malaria eradication is critically dependent on new therapeutics that target resistant Plasmodium parasites and block transmission of the disease. Here, we report that pantothenamide bioisosteres were
Eave ribbons treated with transfluthrin can protect both users and non-users against malaria vectors (Publications)
BACKGROUND: Eave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and could constitute a scalable and low-cost supplem
Collaborative RNAS+ research: priorities and outcomes (Publications)
Over the past 20 years, RNAS(+) has been generating research results from highly collaborative projects meant to promote and advance understanding in various aspects of schistosomiasis. Epidemiologica
The genetic background modulates the evolution of fluoroquinolone-resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Fluoroquinolones (FQ) form the backbone in experimental treatment regimens against drug-susceptible tuberculosis. However, little is known on whether the genetic variation present in natural populatio
Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective... (Publications)
OBJECTIVES: Widespread access to antiretroviral therapy (ART) has substantially increased life expectancy in sub-Saharan African countries. As a result, the rates of comorbidities and use of co-medica
The molecular clock of <em>Mycobacterium tuberculosis</em> (Publications)
The molecular clock and its phylogenetic applications to genomic data have changed how we study and understand one of the major human pathogens, Mycobacterium tuberculosis (MTB), the etiologic agent o
(+/-)-Alternarlactones A and B, two antiparasitic alternariol-like dimers from the fungus <em>Alternaria alternata</em> p1210 isolated from the... (Publications)
Two new dimeric compounds of the alternariol class, (+/-)-alternarlactones A (1) and B (2), were isolated along with 11 known compounds from the fungus Alternaria alternata P1210. Their structures wer
National and sub-national exposure to ambient fine particulate matter PM2.5 and its attributable burden of disease in Iran from 1990 to 2016 (Publications)
Ambient particulate matter is a public health concern. We aimed (1) to estimate national and provincial long-term exposure of Iranians to ambient particulate matter (PM)