2,4-diaminothienopyrimidines as orally active antimalarial agents (Publications)
A novel series of 2,4-diaminothienopyrimidines with potential as antimalarials was identified from whole-cell high-throughput screening of a SoftFocus ion channel library. Synthesis and structure-acti
<em>Paragonimus paishuihoensis</em> metacercariae in freshwater crabs, <em>Potamon lipkei</em>, in Vientiane Province, Lao PDR (Publications)
Among Paragonimus species, P. paishuihoensis is one of the most mysterious and poorly understood species. Metacercariae are characterized by having a unique dendritically branched excretory bladder. H
<em>In vitro</em> efficacy of dicationic compounds and mefloquine enantiomers against <em>Echinococcus multilocularis</em> metacestodes (Publications)
The current chemotherapy of alveolar echinococcosis (AE) is based on benzimidazoles such as albendazole and has been shown to be parasitostatic rather than parasiticidal, requiring lifelong duration.
Effect of sampling and diagnostic effort on the assessment of schistosomiasis and soil-transmitted helminthiasis and drug efficacy: a meta-analysis of... (Publications)
SUMMARY It is generally recommended to perform multiple stool examinations in order to improve the diagnostic accuracy when assessing the impact of mass drug administration programmes to control human
Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II (Publications)
Occupational exposure is a well-recognised modifiable risk factor for asthma, but the relationship between occupational exposure and asthma control has not been studied. We aimed to study this associa
Framework for rapid assessment and adoption of new vector control tools (Publications)
Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidenc
Lymphatic filariasis and onchocerciasis prevention, treatment, and control costs across diverse settings: a systematic review (Publications)
The control and eventual elimination of neglected tropical disease (NTD) requires the expansion of interventions such as mass drug administration (MDA), vector control, diagnostic testing, and effecti
Immunoglobulin A and immunoglobulin G antibodies against beta-lactoglobulin and gliadin at age 1 associate with immunoglobulin E sensitization at age... (Publications)
BACKGROUND: Serum immunoglobulin A (IgA) and immunoglobulin G (IgG) antibodies against wheat gliadin and cow's milk beta-lactoglobulin (BLG) are considered markers of gut permeability and inflammation