Antiprotozoal dimeric naphthylisoquinolines, mbandakamines B3 and B4, and related 5,80'-coupled monomeric alkaloids, ikelacongolines A–D, from a... (Publications)
From the leaves of a botanically and phytochemically as yet unexplored Ancistrocladus liana discovered in the rainforests of the Central region of the Democratic Republic of the Congo in the vicinity
Dental care behaviour in Switzerland (Publications)
Improvements in oral health are changing the requirements for oral health care provision. This study assessed the frequency and major reason of dental visits and personal oral hygiene measures in Swit
Efficacy and safety of ascending dosages of moxidectin and moxidectin-albendazole against <em>Trichuris trichiura</em> in adolescents: a randomized... (Publications)
BACKGROUND: Preventive chemotherapy is the main strategy to control soil-transmitted helminth (STH) infections. Albendazole and Mebendazole are ubiquitously used but they are not sufficiently effectiv
A 5-year intervention study on elimination of urogenital schistosomiasis in Zanzibar: parasitological results of annual cross-sectional surveys (Publications)
BACKGROUND: The Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project aimed to eliminate urogenital schistosomiasis as a public health problem from Pemba and to interrupt Schistosoma hae
Structure–activity relationship and<em> in vitro</em> absorption, distribution, metabolism, excretion, and toxicity (ADMET) studies of <em>N</em>-aryl... (Publications)
We have previously reported on the antischistosomal activity of pyrido [1,2-a] benzimidazole (PBI) derivatives. As a follow-up, we designed and prosecuted further structure-activity relationship (SAR)
Discovery and characterization of <em>Mycobacterium basiliense</em> sp. nov., a nontuberculous <em>Mycobacterium </em>isolated from human lungs (Publications)
Bacteria belonging to the genus Mycobacterium are predominantly responsible for pulmonary diseases; most notably Mycobacterium tuberculosis causes granulomatous pulmonary infections. Here we describe
Safety and efficacy of C-reactive protein-guided antibiotic use to treat acute respiratory infections in Tanzanian children: a planned subgroup... (Publications)
Background: Antibiotic overuse in pediatric primary care in resource-limited settings is driven by respiratory infections. The safety and efficacy of using C-reactive protein (CRP) to decide on antibi
Pooled population pharmacokinetic analysis of tribendimidine for the treatment of <em>Opisthorchis viverrini</em> infections (Publications)
Opisthorchiasis, caused by the food-borne trematode Opisthorchis viverrini, affects more than 8 million people in Southeast Asia. In the framework of a phase 2b clinical trial conducted in Lao PDR, ph