Different strategies to overcome the effect of carbimazole on high- and low-dose radioiodine therapy: results from continuous dose-effect models (Publications)
BACKGROUND: Until now, it remains elusive which strategy - antithyroid drug withdrawal or increased radioiodine target doses - should be preferred to avoid the detrimental effect of antithyroid drugs
The activity of dispiro peroxides against <em>Fasciola hepatica</em> (Publications)
Dispiro 1,2,4-trioxanes and 1,2,4,5-tetraoxanes had superior efficacy against Fasciola hepatica than the corresponding ozonides (1,2,4-trioxolanes). For highest efficacy, spiroadamantane and carboxyme
The PASTURE project: EU support for the improvement of knowledge about risk factors and preventive factors for atopy in Europe (Publications)
Since January 2002, the European Commission is funding a large project, Protection against Allergy - Study in Rural Environments (PASTURE; contract no. QLK4-2001-00250), under the Fifth Framework Prog
Outcome of radioiodine therapy without, on or 3 days off carbimazole: a prospective interventional three-group comparison (Publications)
PURPOSE: Carbimazole ameliorates hyperthyroidism but reduces radioiodine uptake and adversely affects the outcome of simultaneous radioiodine therapy. We explored whether withdrawal of carbimazole for
Evaluation of methods for modeling transcription factor sequence specificity (Publications)
Genomic analyses often involve scanning for potential transcription factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to m