Marginal structural models and other analyses allow multiple estimates of treatment effects in randomized clinical trials: meta-epidemiological... (Publications)
OBJECTIVES: To determine how marginal structural models (MSMs), which are increasingly used to estimate causal effects, are used in randomized clinical trials (RCTs) and compare their results with tho
Ancistrobrevines E-J and related naphthylisoquinoline alkaloids from the West African liana <em>Ancistrocladus abbreviatus</em> with inhibitory... (Publications)
From the roots of the West African liana Ancistrocladus abbreviatus (Ancistrocladaceae), ten new naphthylisoquinoline alkaloids (7a, 7b, 8a, 8b, and 9-14), displaying three different coupling types (5
Antimalarial lead-optimization studies on a 2,6-imidazopyridine series within a constrained chemical space to circumvent atypical dose-response curves... (Publications)
A lead-optimization program around a 2,6-imidazopyridine scaffold was initiated based on the two early lead compounds, 1 and 2, that were shown to be efficacious in an in vivo humanized Plasmodium fal