Essential evidence for guiding health system priorities and policies: anticipating epidemiological transition in Africa (Publications)
Background: Despite indications that infection-related mortality in sub-Saharan Africa may be decreasing and the burden of non-communicable diseases increasing, the overwhelming reality is that health
Estimating population and livestock density of mobile pastoralists and sedentary settlements in the south-eastern Lake Chad area (Publications)
Mobile pastoralists provide major contributions to the gross domestic product in Chad, but little information is available regarding their demography. The Lake Chad area population is increasing, resu
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion (Publications)
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50?0.5 µM), and was posited to exploit the physiological differen
Near-roadway pollution and childhood asthma: implications for developing "win-win" compact urban development and clean vehicle strategies (Publications)
BACKGROUND: The emerging consensus that exposure to near-roadway traffic-related pollution causes asthma has implications for compact urban development policies designed to reduce driving and greenhou
Adult non-communicable disease mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
BACKGROUND: Mortality from non-communicable diseases (NCDs) is a major global issue, as other categories of mortality have diminished and life expectancy has increased. The World Health Organization's
Eleganolone, a Diterpene from the French marine alga <em>Bifurcaria bifurcata</em> inhibits growth of the human pathogens <em>Trypanosoma brucei</em>... (Publications)
Organic extracts of 20 species of French seaweed have been screened against Trypanosoma brucei rhodesiense trypomastigotes, the parasite responsible for sleeping sickness. These extracts have previous
Novel <em>Mycobacterium tuberculosis</em> complex isolate from a wild chimpanzee (Publications)
Tuberculosis (TB) is caused by gram-positive bacteria known as the Mycobacterium tuberculosis complex (MTBC). MTBC include several human-associated lineages and several variants adapted to domestic an
Antiprotozoal activity of <em>Achillea ptarmica</em> (Asteraceae) and its main alkamide constituents (Publications)
In the course of our ongoing screening of plants of the family Asteraceae for antiprotozoal activity, a CH2Cl2-extract from the flowering aerial parts of Achillea ptarmica L. (sneezewort yarrow) was f
Background ionizing radiation and the risk of childhood cancer: a census-based nationwide cohort study (Publications)
BACKGROUND: Exposure to medium or high doses of ionizing radiation is a known risk factor for cancer in children. The extent to which low-dose radiation from natural sources contributes to the risk of
Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa (Publications)
Factors driving the increase in drug-resistant tuberculosis (TB) in the Eastern Cape Province, South Africa, are not understood. A convenience sample of 309 drug-susceptible and 342 multidrug-resistan