Cancer risk assessment of selected hazardous air pollutants in Seattle (Publications)
The risk estimates calculated from the conventional risk assessment method usually are compound specific and provide limited information for source-specific air quality control. We used a risk apporti
Potential long-term toxicity of repeated orally administered doses of artemether in rats (Publications)
Artemether, an efficacious antimalarial drug, effectively prevents patent schistosome infections and morbidity, as established in laboratory models and in clinical trials. In view of concern about the
Identification of fecal input sites in spring water by selection and genotyping of multiresistant <em>Escherichia coli</em> (Publications)
The localization of fecal input sites is important for water quality management. For this purpose, we have developed a new approach based on a three-step procedure, including a preparatory phase, the
Effect of single-dose oral artemether and tribendimidine on the tegument of adult <em>Clonorchis sinensis</em> in rats (Publications)
The tegument of trematodes plays a key role in nutrient absorption, exerts secretory functions, protects the parasite against the immune system of the host, and is a target for anti-trematocidal drugs
dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors (Publications)
Pyrimidine metabolism is a major route for therapeutic intervention against malaria. Here we report inhibition and structural studies on the deoxyuridine nucleotidohydrolase from the malaria parasite