Insufficient fruit and vegetable intake in a low- and middle-income setting: a population-based survey in semi-urban Tanzania (Publications)
A daily intake of 5 portions of fruit and vegetables (FV) is recommended for protection against non-communicable diseases (NCDs). Inadequate FV intake is a global problem but resource-poor countries l
Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus <em>Geomyces auratus</em> (Publications)
Georatusin (1), featuring a highly reduced, methylated polyketide moiety fused to a tryptophan by an amide and ester bond forming a 13-membered ring, was produced by the soil fungus Geomyces auratus.
High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds (Publications)
Rapidly spreading antibiotic resistance and the low discovery rate of new antimicrobial compounds demand more effective strategies for early drug discovery. One bottleneck in the drug discovery pipeli
Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic... (Publications)
African trypanosomiasis is a neglected parasitic disease that is still of great public health relevance, and a severe impediment to agriculture in endemic areas. The pathogens possess certain unique m
Impact and cost-effectiveness of snail control to achieve disease control targets for schistosomiasis (Publications)
Schistosomiasis is a parasitic disease that affects over 240 million people globally. To improve population-level disease control, there is growing interest in adding chemical-based snail control inte
Microbiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction (Publications)
Background: Endoscopic lung volume reduction (eLVR) is a therapeutic option for selected patients with COPD and severe emphysema. Infectious exacerbations are serious events in these vulnerable patien