If you can't measure it- you can't change it - a longitudinal study on improving quality of care in hospitals and health centers in rural... (Publications)
BACKGROUND: The Kenyan Ministry of Health- Department of Standards and Regulations sought to operationalize the Kenya Quality Assurance Model for Health. To this end an integrated quality management s
Biological evaluation and x-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox... (Publications)
The tropical diseases human African trypanosomiasis, Chagas disease, and the various forms of leishmaniasis are caused by parasites of the family of trypanosomatids. These protozoa possess a unique re
GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing (Publications)
Malaria is caused by Plasmodium parasites that proliferate in the bloodstream. During each replication cycle, some parasites differentiate into gametocytes, the only forms able to infect the mosquito
Airway responsiveness to methacholine and incidence of COPD: an international prospective cohort study (Publications)
BACKGROUND: It has been debated, but not yet established, whether increased airway responsiveness can predict COPD. Recognising this link may help in identifying subjects at risk. OBJECTIVE: We studie
Total synthesis and biological investigation of (-)-artemisinin: the antimalarial activity of artemisinin is not stereospecific (Publications)
Here, we describe an efficient and diversity oriented entry to both (-)-artemisinin (1) and to its natural antipode (+)-artemisinin starting from commercially and readily available S-(+)- and R-(-)-ci
Telemedicine for health issues while abroad: interest and willingness to pay among travellers prior to departure (Publications)
Background: Telemedicine is emerging as a useful tool to provide expert medical advice to individuals facing health issues while travelling in remote areas. Before embarking on the development of a te
Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity (Publications)
BACKGROUND: Large sequence datasets are difficult to visualize and handle. Additionally, they often do not represent a random subset of the natural diversity, but the result of uncoordinated and conve
Analysis of clinical drug-drug interaction data to predict uncharacterized interaction magnitudes between antiretroviral drugs and co-medications (Publications)
Despite their high potential for drug-drug-interactions (DDI), clinical DDI studies of antiretroviral drugs (ARVs) are often lacking, because the full range of potential interactions cannot feasibly o