Better data for better outcomes: the importance of process mapping and management in CRVS systems (Publications)
BACKGROUND: Despite attempts to apply standard methods proven to work in high-income nations, nearly all civil registration and vital statistics (CRVS) systems in low- and middle-income countries are
Discovery and optimization of a compound series active against <em>Trypanosoma cruzi</em>, the causative agent of chagas disease (Publications)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. It is endemic in South and Central America and recently has been found in other parts of the world, due to migration of chronicall
Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in <em>Trypanosoma brucei</em> (Publications)
Suramin was introduced into the clinic a century ago and is still used to treat the first stage of acute human sleeping sickness. Due to its size and sixfold negative charge, uptake is mediated throug
Applied mathematical modelling to inform national malaria policies, strategies and operations in Tanzania (Publications)
BACKGROUND: More than ever, it is crucial to make the best use of existing country data, and analytical tools for developing malaria control strategies as the heterogeneity in malaria risk within coun
Effects of transportation noise and particulate matter on the cardiovascular system: what is the new evidence? (Publications)
SUMMARY: Several decades of research provides compelling evidence that exposure to air pollution causes various diseases. Time series studies in Europe and the USA examined the short term effects on m
Prospective assessment of loss to follow-up: incidence and associated factors in a cohort of HIV-positive adults in rural Tanzania (Publications)
INTRODUCTION: Lifelong antiretroviral therapy (ART) improves health outcomes for HIV-positive individuals, but is jeopardized by irregular clinic attendance and hence poor adherence. Loss to follow-up
Use of insecticides in agriculture and the prevention of vector-borne diseases: population knowledge, attitudes, practices and beliefs in Elibou,... (Publications)
People's knowledge, attitudes, practices and beliefs (KAPB) pertaining to malaria are generally well described. However, little is known about population knowledge and awareness of insecticide resista
TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like <em>Mycobacterium tuberculosis</em> (Publications)
TNF-alpha- as well as non-TNF-alpha-targeting biologics are prescribed to treat a variety of immune-mediated inflammatory disorders. The well-documented risk of tuberculosis progression associated wit
The fight against lymphatic filariasis: perceptions of community drug distributors during mass drug administration in coastal Kenya (Publications)
BACKGROUND: Lymphatic filariasis (LF), a neglected tropical disease (NTD) and leading cause of global disability, is endemic in 32 countries in Africa with almost 350 million people requiring regular