Asthma and the menopause: a systematic review and meta-analysis (Publications)
OBJECTIVE: To review the available literature to determine whether the menopausal transition is associated with asthma incidence.METHODS: We performed a systematic review and meta-analysis of cohort a
Predictors of methacholine responsiveness in a general population (Publications)
OBJECTIVE: Methacholine responsiveness is an end point widely used in epidemiologic studies of asthma. This study aims to quantify the relative importance of different predictors of responsiveness suc
Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population (Publications)
ABSTRACT: BACKGROUND: Few epidemiologic studies have assessed health-related quality of life (HRQL) of asthma patients from a general population and it is unclear which instrument is best suitable for
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (T
Defining the next generation of <em>Plasmodium vivax</em> diagnostic tests for control and elimination: target product profiles (Publications)
The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional ma
Development and evaluation of a bioinformatics approach for designing molecular assays for viral detection (Publications)
BACKGROUND: Viruses belonging to the Flaviviridae and Bunyaviridae families show considerable genetic diversity. However, this diversity is not necessarily taken into account when developing diagnosti
IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population (Publications)
Within the framework of the SAPALDIA survey (Swiss study on Air Pollution and Lung Diseases in Adults), we studied the influence of sex, age and smoking habits on total serum IgE and allergen-specific
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants (Publications)
Chronic obstructive pulmonary disease (COPD) is a prevalent and preventable disease associated with high morbidity and mortality. Severe and intermediate alpha1-antitrypsin (AAT) deficiency (serum lev
What physical activity surveillance needs: validity of a single-item questionnaire (Publications)
BACKGROUND: Self-report instruments to assess physical activity are still the most feasible option in many population-wide surveys, and often need to be very short owing to resource constraints. The a