Probing <em>Plasmodium falciparum</em> sexual commitment at the single-cell level (Publications)
Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure. Here we apply single cell transcriptomics to unr
Analysis of potential household transmission events of tuberculosis in the city of Belem, Brazil (Publications)
Tuberculosis (TB) is an infectious disease with a higher risk for infection and disease among household contacts (HHC). Here, we report a molecular epidemiology-based approach to study disease transmi
Seroprevalence and herd-level risk factors for seroprevalence of <em>Leptospira</em> spp. in sheep, beef cattle and deer in New Zealand (Publications)
AIMS To determine seroprevalence of Leptospira borgpetersenii serovar Hardjo and L. interrogans serovar Pomona in beef cattle, sheep and deer in New Zealand and the association between farm-level risk
Transportation noise exposure, noise annoyance and respiratory health in adults: a repeated-measures study (Publications)
Transportation noise leads to sleep disturbance and to psychological and physiological sustained stress reactions, which could impact respiratory health. However, epidemiologic evidence on association
Comparative pan-genomic analyses of <em>Orientia tsutsugamushi </em>reveal an exceptional model of bacterial evolution driving genomic diversity (Publications)
Orientia tsutsugamushi, formerly Rickettsia tsutsugamushi, is an obligate intracellular pathogen that causes scrub typhus, an underdiagnosed acute febrile disease with high morbidity. Scrub typhus is
Novel high-throughput screening method using quantitative PCR to determine the antimicrobial susceptibility of <em>Orientia tsutsugamushi... (Publications)
Objectives: To develop a method to enable the large-scale antimicrobial susceptibility screening of Orientia tsutsugamushi clinical isolates, using one timepoint and one concentration of antibiotics t
Case report: concurrent sympatric scrub typhus and Japanese spotted fever in Japan (Publications)
Scrub typhus and Japanese spotted fever-both rickettsial diseases-are endemic and notifiable in Japan and may cause a fatal outcome without prompt treatment. Here we present the first case of a concur
Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in... (Publications)
BACKGROUND: The RTS,S/AS01E vaccine provides partial protection against malaria in African children, but immune responses have only been partially characterized and do not reliably predict protective
Environmental and health data needed to develop national surveillance systems in industrially contaminated sites (Publications)
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Public health surveillance (PHS) of industrially contaminated sites (ICSs) is likely to play a role in supporting the monitoring of