Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a... (Publications)
BACKGROUND: Accurate, scalable and sensitive diagnostic tools are crucial in determining prevalence of soil-transmitted helminths (STH), assessing infection intensities and monitoring treatment effica
The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines (Publications)
Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which seriously affects human health in A
Dental and periodontal health in a Swiss population-based sample of older adults: a cross-sectional study (Publications)
In this cross-sectional study, the prevalences of tooth loss, prosthetic dental restorations, and probing pocket depths (PPDs) of ≥4 mm, and their relationship to sociodemographic factors, were invest
Initial characterisation of commercially available ELISA tests and the immune response of the clinically correlated SARS-CoV-2 biobank... (Publications)
Background To accurately measure seroprevalance in the population, both the expected immune response as well as the assay performances have to be well characterised. Here, we describe the collection a
An interdisciplinary centre of excellence for pastoralists in the Horn of Africa (Publications)
The specific needs of nomadic pastoralist communities are often not considered in public services. This is also the case in the health sector. In Ethiopia, Swiss Development Cooperation is supporting
One Health - towards a more inclusive science (Publications)
How can we move in the direction of a modern theory of health that has the ability to face the new complex challenges of global change? The One Health concept suggests that health must be viewed as th
Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a (Publications)
Limited therapeutic options are available for the treatment of human schistosomiasis caused by the parasitic Schistosoma flatworm. The B cell lymphoma-2 (BCL-2)-regulated apoptotic cell death pathway
Quest for a potent antimalarial drug lead: synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines (Publications)
Quinazolines have long been known to exert varied pharmacologic activities that make them suitable for use in treating hypertension, viral infections, tumors, and malaria. Since 2014, we have synthesi