Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against <em>Leishmania</em> and... (Publications)
Aminoglycoside antibiotics target the ribosomal decoding A-site and are active against a broad spectrum of bacteria. These compounds bind to a highly conserved stem-loop-stem structure in helix 44 of
Tick-borne diseases in Switzerland and climate change (Publications)
Tick-borne diseases are the most common vector-borne diseases in Europe. In Central Europe, the tick Ixodes ricinus is responsible for most tick bites. Next to tick borne encephalitis (TBE or in Germa
Understanding and improving access to prompt and effective malaria treatment and care in rural Tanzania: the ACCESS Programme (Publications)
BACKGROUND: Prompt access to effective treatment is central in the fight against malaria. However, a variety of interlinked factors at household and health system level influence access to timely and
Toward an open-access global database for mapping, control, and surveillance of neglected tropical diseases (Publications)
BACKGROUND: After many years of general neglect, interest has grown and efforts came under way for the mapping, control, surveillance, and eventual elimination of neglected tropical diseases (NTDs). D
Malaria and its possible control on the island of Príncipe (Publications)
BACKGROUND: Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalen
Rifampicin/Cotrimoxazole/Isoniazid versus mefloquine or quinine + sulfadoxine- pyrimethamine for malaria: a randomized trial1 (Publications)
OBJECTIVES: Previous studies of a fixed combination including cotrimoxazole, rifampicin, and isoniazid (Cotrifazid) showed efficacy against resistant strains of Plasmodium falciparum in animal models