Field comparison of circulating antibody assays <em>versus</em> circulating antigen assays for the detection of <em>Schistosomiasis japonica</em> in... (Publications)
BACKGROUND: Schistosomiasis remains a serious public health problem in affected countries, and routine, highly sensitive and cost-effective diagnostic methods are lacking. We evaluated two immunodiagn
Modelling heterogeneity in malaria transmission using large sparse spatio-temporal entomological data (Publications)
Background: Malaria transmission is measured using entomological inoculation rate (EIR), number of infective mosquito bites/person/unit time. Understanding heterogeneity of malaria transmission has be
Experimental infection of the pig with <em>Mycobacterium ulcerans</em>: a novel model for studying the pathogenesis of Buruli ulcer disease (Publications)
BACKGROUND: Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, w
<em>Plasmodium falciparum </em>infection and clinical indicators in relation to net coverage in central Côte d'Ivoire (Publications)
BACKGROUND: Sleeping under a net, particularly a long-lasting insecticidal net (LLIN), is associated with reduced malaria morbidity and mortality, but requires high coverage and adherence. In this stu
Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against <em>Schistosoma haematobium</em>: a randomized, exploratory,... (Publications)
BACKGROUND: Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The an
Progress in mosquito net coverage in Papua New Guinea (Publications)
BACKGROUND: Since 2004, the Global Fund-supported National Malaria Control Programme of Papua New Guinea (PNG) has been implementing country-wide free long-lasting insecticidal net (LLIN) distribution
A cluster-randomized controlled trial to assess the effectiveness of using 15% DEET topical repellent with long-lasting insecticidal nets (LLINs)... (Publications)
BACKGROUND: Long-lasting insecticidal nets (LLINs) have limited effect on malaria transmitted outside of sleeping hours. Topical repellents have demonstrated reduction in the incidence of malaria tran
Effect of home-based counselling on newborn care practices in southern Tanzania one year after implementation: a cluster-randomised controlled trial (Publications)
BACKGROUND: In Sub-Saharan Africa over one million newborns die annually. We developed a sustainable and scalable home-based counselling intervention for delivery by community volunteers in rural sout