Limited antigenic diversity of <em>Plasmodium falciparum</em> apical membrane antigen 1 supports the development of effective multi-allele vaccines (Publications)
BackgroundPolymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine development. In malaria, many key immune targets
Identification of the <em>Mycobacterium ulcerans</em> protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer (Publications)
Buruli ulcer (BU) caused by Mycobacterium ulcerans is a devastating skin disease, occurring mainly in remote West African communities with poor access to health care. Early case detection and subseque
Simple fecal flotation is a superior alternative to guadruple kato katz smear examination for the detection of hookworm eggs in human stool (Publications)
BACKGROUND: Microscopy-based identification of eggs in stool offers simple, reliable and economical options for assessing the prevalence and intensity of hookworm infections, and for monitoring the su
Potential risk of regional disease spread in west Africa through cross-border cattle trade (Publications)
BACKGROUND: Transboundary animal movements facilitate the spread of pathogens across large distances. Cross-border cattle trade is of economic and cultural importance in West Africa. This study explor
Impact of home environment interventions on the risk of influenza-associated ARI in Andean children: observations from a prospective household-based... (Publications)
BACKGROUND:The Respiratory Infections in Andean Peruvian Children (RESPIRA-PERU) study enrolled children who participated in a community-cluster randomized trial of improved stoves, solar water disinf
Study protocol: improving newborn survival in rural southern Tanzania: a cluster-randomised trial to evaluate the impact of a scaleable package of... (Publications)
Child mortality has declined substantially in many countries including Tanzania, but newborn mortality remains high and around 3 million babies die every year in the first 28 days of life. Community-b
Improving health worker adherence to malaria treatment guidelines in Papua New Guinea: feasibility and acceptability of a text message reminder... (Publications)
The aim of this study is to assess whether a text message reminder service designed to support health worker adherence to a revised malaria treatment protocol is feasible and acceptable in Papua New G