An atypical mitochondrial carrier that mediates drug action in <em>Trypanosoma brucei</em> (Publications)
Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library
A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic... (Publications)
BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, the number of affected individuals is rising, with significant impacts for healthcare systems. Current symptomatic treatments
Childhood illness prevalence and health seeking behavior patterns in rural Tanzania (Publications)
INTRODUCTION: This paper identifies factors influencing differences in the prevalence of diarrhea, fever and acute respiratory infection (ARI), and health seeking behavior among caregivers of children
A single-nucleotide-polymorphism real-time PCR assay for genotyping of <em>Mycobacterium tuberculosis</em> complex in peri-urban Kampala (Publications)
BACKGROUND: Accurate and high-throughput genotyping of Mycobacterium tuberculosis complex (MTBC) may be important for understanding the epidemiology and pathogenesis of tuberculosis (TB). In this stud
Larval and adult environmental temperatures influence the adult reproductive traits of <em>Anopheles gambiae</em> s.s. (Publications)
BACKGROUND: Anopheles mosquito life-history parameters and population dynamics strongly influence malaria transmission, and environmental factors, particularly temperature, strongly affect these param