Job strain associated CRP is mediated by leisure time physical activity: results from the MONICA/KORA study (Publications)
BACKGROUND: Psychological stress at work is considered a cardiac risk factor, yet whether it acts directly through neuroimmune processes, or indirectly by increasing behavioral risk factors, is uncert
Decline in gait performance detected by an electronic walkway system in 907 older adults of the population-based KORA-age study (Publications)
Background: Gait changes at older ages are a strong predictor of a decline in lower extremity functions. However, large population-based studies assessing gait parameters in various gait tasks are lac
Association between physical activity and risk of stroke subtypes: the atherosclerosis risk in communities study (Publications)
BACKGROUND: The relationship between stroke subtypes and physical activity is unclear. METHODS: Using data from 13,069 men and women aged 45-64 years who participated in the Atherosclerosis Risk in Co
Antiparasitic drugs for paediatrics: systematic review, formulations, pharmacokinetics, safety, efficacy and implications for control (Publications)
SUMMARYDrug development for paediatric applications entails a number of challenges, such as the wide age spectrum covered - from birth to adolescence - and developmental changes in physiology during b
New drugs for the treatment of human African trypanosomiasis: research and development (Publications)
Chemotherapy of human African trypanosomiasis is problematic because of the high frequency of severe adverse events, the long duration and high cost of treatment, and an increasing number of treatment
Topoisomerases in kinetoplastids (Publications)
Topoisomerases are enzymes that mediate topological changes in DNA that are essential for nucleic acid biosynthesis and for cell survival. The kinetoplastid protozoa, which include pathogenic trypanos