Effects of engaging communities in decision-making and action through traditional and religious leaders on vaccination coverage in Cross River State,... (Publications)
BACKGROUND: Vaccination coverage levels fall short of the Global Vaccine and Action Plan 90% target in low- and middle- income countries (LMICs). Having identified traditional and religious leaders (T
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate... (Publications)
Dihydroorotate dehydrogenase (DHODH) has been clinically validated as a target for the development of new antimalarials. Experience with clinical candidate triazolopyrimidine DSM265 (1) suggested that
Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as <em>Plasmodium </em>cytoplasmic prolyl-trna synthetase... (Publications)
Prolyl-tRNA synthetase (PRS) is a clinically validated antimalarial target. Screening of a set of PRS ATP-site binders, initially designed for human indications, led to identification of 1-(pyridin-4-
Health in food systems policies in India: a document review (Publications)
BACKGROUND: Food systems affect nutritional and other health outcomes. Recent literature from India has described policy aspects addressing nutritional implications of specific foods (eg, fruits, vege
Human behavior, livelihood, and malaria transmission in two sites of Papua New Guinea (Publications)
BACKGROUND: Malaria transmission is currently resurging in Papua New Guinea (PNG). In addition to intervention coverage, social and cultural factors influence changes in epidemiology of malaria in PNG
Common haplotypes at the <em>CFH </em>locus and low-frequency variants in <em>CFHR2 </em>and <em>CFHR5 </em>associate with systemic FHR concentrations... (Publications)
Age-related macular degeneration (AMD) is the principal cause of blindness in the elderly population. A strong effect on AMD risk has been reported for genetic variants at the CFH locus, encompassing
Two-target quantitative PCR to predict library composition for shallow shotgun sequencing (Publications)
When determining human microbiota composition, shotgun sequencing is a powerful tool that can generate high-resolution taxonomic and functional information at once. However, the technique is limited b
Quantifying transmission fitness costs of multi-drug resistant tuberculosis (Publications)
As multi-drug resistant tuberculosis (MDR-TB) continues to spread, investigating the transmission potential of different drug-resistant strains becomes an ever more pressing topic in public health. Wh
Associations of air pollution and greenness with the nasal microbiota of healthy infants: a longitudinal study (Publications)
BACKGROUND: Air pollution and greenness are associated with short- and long-term respiratory health in children but the underlying mechanisms are only scarcely investigated. The nasal microbiota durin