Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (
Fleischkonsum und Serum-Cholesterin-Konzentration (Publications)
In a representative cross-sectional study of the population of Basel, Switzerland (252 men, 281 women, mean age 48 25-74 years), there was a significant association between the consumption of meat and
Treatment of cutaneous leishmaniasis among travellers (Publications)
Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over
Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community (Publications)
INTRODUCTION: Lower prevalence rates of allergic diseases in rural as compared with urban populations have been interpreted as indicating an effect of air pollution. However, little is known about oth
Der Wurm im Gehirn (Publications)
Cerebral signs of focalized infection or tumour with changing localisation or meningoencephalitis with a travel history should alert the clinician to consider the possibility of a worm infection. A de
Human African trypanosomiasis in endemic populations and travellers (Publications)
Human African trypanosomiasis (HAT) or sleeping sickness is caused by the protozoan parasites Trypanosoma brucei (T.b.) gambiense (West African form) and T.b. rhodesiense (East African form) that are