Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study (Publications)
Many studies have demonstrated an association of both a sedentary lifestyle and a high body mass index (BMI) with greater risk for cardiovascular disease. Within the prospective SAPALDIA cohort (Swiss
Synthesis and antiplasmodial activity of new N-[3-(4-{3-[(7-chloroquinolin-4-yl)amino]propyl}piperazin-1-yl)propyl]carboxamides (Publications)
The parallel acylation of N-{3-[4-(3-aminopropyl)piperazin-1-yl]propyl}-7-chloroquinolin-4-amine with polymer-bound carboxylic acids opened straightforward access to novel aminoquinolines with activit
Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian <em>Didemnum</em> sp (Publications)
Two new indole spermidine alkaloids, didemnidines A (1) and B (2), have been isolated from the New Zealand ascidian Didemnum sp. The structures of the metabolites, determined by analysis of 2D NMR spe
<em>Mycobacterium tuberculosis</em> transmission in a country with low tuberculosis incidence: role of immigration and HIV infection (Publications)
Immigrants from high-burden countries and HIV-coinfected individuals are risk groups for tuberculosis (TB) in countries with low TB incidence. Therefore, we studied their role in transmission of Mycob
Predictors of state-of-the-art management of early breast cancer in Switzerland (Publications)
Background: The aim of this study was to investigate predictors of state-of-the-art management of early breast cancer in Switzerland. PATIENTS AND METHODS: The study included 3499 women aged 25-79 yea
Differences in heart rate variability associated with long-term exposure to NO2 (Publications)
BACKGROUND: Heart rate variability (HRV), a measure of cardiac autonomic tone, has been associated with cardiovascular morbidity and mortality. Short-term studies have shown that subjects exposed to h
Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines (Publications)
A novel series of extended DAPI analogues were prepared by insertion of either a carbon-carbon triple bond (16a-d) or a phenyl group (21a, b and 24) at position-2. The new amidines were evaluated in v