Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of <em>Plasmodium falciparum</em> dUTP... (Publications)
The ubiquitous enzyme dUTP nucleotidohydrolase (dUTPase) catalyses the hydrolysis of dUTP to dUMP and can be considered as the first line of defence against incorporation of uracil into DNA. Inhibitio
Quantification of self pollution from two diesel school buses using three independent methods (Publications)
We monitored two Seattle school buses to quantify the buses' self pollution using the dual tracers (DT), lead vehicle (LV), and chemical mass balance (CMB) methods. Each bus drove along a residential
Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites (Publications)
Non-functional analogs of the cofactors ATP and NAD are putative inhibitors of ATP- or NAD-dependant enzymes. Since pathogenic protozoa rely heavily on the salvage of purine nucleosides from the blood
Comparison of light scattering devices and impactors for particulate measurements in indoor, outdoor, and personal environments (Publications)
Short-term monitoring of individual particulate matter (PM) exposures on subjects and inside residences in health effect studies have been sparse due to the lack of adequate monitoring devices. The re
Characterization of source-specific air pollution exposure for a large population-based Swiss cohort (SAPALDIA) (Publications)
BACKGROUND: Although the dispersion model approach has been used in some epidemiologic studies to examine health effects of traffic-specific air pollution, no study has evaluated the model predictions
Epidemiology of <em>Schistosoma japonicum</em> in China: morbidity and strategies for control in the Dongting Lake region (Publications)
Dongting Lake, covering a very large surface water area of 2691km(2), is located in Hunan Province in the southern part of the People's Republic of China. It is the second-largest freshwater lake in C