Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (T
Defining the next generation of <em>Plasmodium vivax</em> diagnostic tests for control and elimination: target product profiles (Publications)
The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional ma
Development and evaluation of a bioinformatics approach for designing molecular assays for viral detection (Publications)
BACKGROUND: Viruses belonging to the Flaviviridae and Bunyaviridae families show considerable genetic diversity. However, this diversity is not necessarily taken into account when developing diagnosti
Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers (Publications)
BACKGROUND: Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are
IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population (Publications)
Within the framework of the SAPALDIA survey (Swiss study on Air Pollution and Lung Diseases in Adults), we studied the influence of sex, age and smoking habits on total serum IgE and allergen-specific
Ten-year follow-up of cluster-based asthma phenotypes in adults: a pooled analysis of three cohorts (Publications)
Rationale: The temporal stability of adult asthma phenotypes identified using clustering methods has never been addressed. Longitudinal cluster-based methods may provide novel insights in the study of
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants (Publications)
Chronic obstructive pulmonary disease (COPD) is a prevalent and preventable disease associated with high morbidity and mortality. Severe and intermediate alpha1-antitrypsin (AAT) deficiency (serum lev
What physical activity surveillance needs: validity of a single-item questionnaire (Publications)
BACKGROUND: Self-report instruments to assess physical activity are still the most feasible option in many population-wide surveys, and often need to be very short owing to resource constraints. The a
Can community health workers play a greater role in increasing access to medical abortion services? A qualitative study (Publications)
BACKGROUND: Despite being legally available in India since 1971, barriers to safe and legal abortion remain, and unsafe and/or illegal abortion continues to be a problem. Community health workers have
Interventions that effectively target <em>Anopheles funestus</em> mosquitoes could significantly improve control of persistent malaria transmission in... (Publications)
Malaria is transmitted by many Anopheles species whose proportionate contributions vary across settings. We re-assessed the roles of Anopheles arabiensis and Anopheles funestus, and examined potential