<em>Trypanothione reductase</em> high-throughput screening campaign identifies novel classes of inhibitors with anti-parasitic activity (Publications)
A high-throughput screening campaign of 100,000 lead like compounds led to the identification of 9 novel chemical classes of trypanothione reductase (TR) inhibitors worthy of further investigation. Hi
Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for Human African Trypanosomiasis (HAT) (Publications)
We previously reported the discovery of the activity of chloronitrobenzamides (CNBs) against bloodstream forms of Trypanosoma brucei . Herein we disclose extensive structure-activity relationship and
Effectiveness of a comprehensive schistosomiasis japonica control program in Jiangsu province, China, from 2005 to 2008 (Publications)
The effectiveness of a comprehensive schistosomiasis japonica control program implemented in 8 villages along the Yangtze river in Jiangsu province from 2005 to 2008 was studied. Control measures incl
Real-time PCR detection and quantification of vector trichodorid nematodes and <em>Tobacco rattle virus</em> (Publications)
This report describes a novel diagnostic method for virus-vector trichodorid nematodes and associated Tobacco rattle virus (TRV) based on a real-time fluorogenic 5' nuclease PCR assay (TaqMan). Two in