Cardiac alterations in human African trypanosomiasis (<em>T.b. gambiense</em>) with respect to the disease stage and antiparasitic treatment (Publications)
BACKGROUND: In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds
Phylogeography and taxonomy of <em>Trypanosoma brucei</em> (Publications)
BACKGROUND: Characterizing the evolutionary relationships and population structure of parasites can provide important insights into the epidemiology of human disease. METHODOLOGY/PRINCIPAL FINDINGS: W
Patient's site of first access to health system influences length of delay for tuberculosis treatment in Tajikistan (Publications)
ABSTRACT: BACKGROUND: Tajikistan has the highest incidence rate of tuberculosis (TB) in Central Asia. Its health system still bears many features from Soviet times and is under-funded. Affordability i
Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control (Publications)
BACKGROUND: Whiles awaiting for the arrival of an effective and affordable malaria vaccine, there is a need to make use of the available control tools to reduce malaria risk, especially in children un
Health services for Buruli ulcer control: lessons from a field study in Ghana (Publications)
BACKGROUND: Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, is a debilitating disease of the skin and underlying tissue. The first phase of a BU prevention and treatment programme (BUPa
The incidence of malaria in travellers to South-East Asia: is local malaria transmission a useful risk indicator? (Publications)
BACKGROUND: The presence of ongoing local malaria transmission, identified though local surveillance and reported to regional WHO offices, by S-E Asian countries, forms the basis of national and inter
Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent... (Publications)
BACKGROUND: The study describes the molecular epidemiology of Streptococcus pneumoniae causing invasive disease in Gambian children METHODS: One hundred and thirty-two S. pneumoniae isolates were reco
Comparative genomics of the anopheline glutathione s-transferase epsilon cluster (Publications)
Enzymes of the glutathione S-transferase (GST) family play critical roles in detoxification of xenobiotics across many taxa. While GSTs are ubiquitous both in animals and plants, the GST epsilon class
Detectability of <em>Plasmodium falciparum</em> clones (Publications)
ABSTRACT: BACKGROUND: In areas of high transmission people often harbour multiple clones of Plasmodium falciparum, but even PCR-based diagnostic methods can only detect a fraction (the detectability,
Achieving high coverage of larval-stage mosquito surveillance: challenges for a community-based mosquito control programme in urban Dar es Salaam,... (Publications)
BACKGROUND: Preventing malaria by controlling mosquitoes in their larval stages requires regular sensitive monitoring of vector populations and intervention coverage. The study assessed the effectiven