Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study (Publications)
A higher incidence of asthma is reported in women compared with men, but evidence in later adulthood is limited. We aimed to determine the 20-year cumulative incidence of adult asthma in Switzerland a
Re-estimated equations for 5th percentiles of lung function variables (Letter to editors) (Publications)
In 1996 we published reference equations for the 5th percentiles of lung function parameters (FVC, FEV1, PEF, FEF25, FEF50, FEF75, FEF25-75, FEV1/FVC) as a function of age and height.1 These reference
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function (Publications)
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 seco
Long-term smoking cessation and heart rate dynamics in an aging healthy cohort: is it possible to fully recover? (Publications)
AIM: To evaluate the long-term influence of smoking cessation on the regulation of the autonomic cardiovascular system in an aging general population, using the subpopulation of lifelong non-smokers a
Agreement between spirometers: a challenge in the follow-up of patients and populations? (Publications)
Background: Long-term cohort studies and lung function laboratories are confronted with the need for replacement of spirometers. Lack of agreement between spirometers might affect the longitudinal com
Variability and reproducibility of carotid structural and functional parameters assessed with transcutaneous ultrasound - results from the SAPALDIA... (Publications)
OBJECTIVE: Carotid intima media thickness (CIMT) and local stiffness are vascular biomarkers of atherosclerotic burden. We investigated the variability and reproducibility of clinically relevant struc
Differences in indoor versus outdoor concentrations of ultrafine particles, PM2.5, PMabsorbance and NO2 in Swiss homes (Publications)
Indoor air quality is a growing concern as we spend the majority of time indoors and as new buildings are increasingly airtight for energy saving purposes. For a better understanding of residential in
Biobanking across the phenome - at the center of chronic disease research (Publications)
BACKGROUND: Recognized public health relevant risk factors such as obesity, physical inactivity, smoking or air pollution are common to many non-communicable diseases (NCDs). NCDs cluster and co-morbi
Longitudinal change of prebronchodilator spirometric obstruction and health outcomes: results from the SAPALDIA cohort (Publications)
Background Understanding the prognostic meaning of early stages of chronic obstructive pulmonary disease (COPD) in the general population is relevant for discussions about underdiagnosis. To date, COP