Efficacy and safety of fexinidazole in patients with Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense: a multicentre,... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/efficacy-and-safety-of-fexinidazole-in-patients-with-human-african-trypanosomiasis-hat-due-to-trypanosoma-brucei-rhodesiense-a-multicentre-open-label-clinical-trial
A vector-borne parasitic illness, human African trypanosomiasis (HAT), also known as sleeping sickness, is usually fatal without treatment. The less prevalent form, T.b. rhodesiense (r-HAT), is concen
Promoting platinum open access for low and middle income country scientists: A publication fee waiver program for two Swiss society journals (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/promoting-platinum-open-access-for-low-and-middle-income-country-scientists-a-publication-fee-waiver-program-for-two-swiss-society-journals
scientists from low and middle income and from some countries in economic transition (LMIC+) with platinum open access (OA) 2022-2024 in the International Journal of Public Health (IJPH) and Public Health Reviews [...] LMIC+ researchers to publish in closed access journals where their research does not receive the same open reach. Alternatively, they must place HIC co-authors as first or corresponding authors to get free [...] cover the publication fees for authors who do not qualify for other...
Global online training course for openIMIS (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/global-online-training-course-for-openimis
to the manifold OpenIMIS capacity building elements, by optimizing their structure, integrating them in a modular learning package and making them available as a self-paced certified OpenIMIS e-learning [...] well as new members of the OpenIMIS community on using the software. Contents and formats of the global implementation support will shape and convey the spirit of an engaging OpenIMIS community and its capacity [...] engaged stakeholders increases, adding to the organizational complexity of...
Massive Open Online Course on Insecticide Resistance Management (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/massive-open-online-course-on-insecticide-resistance-management
developing an online IRM training course or ‘MOOC’ (Massive Online Open Course). The IRM MOOC will be free for the participant and open to anyone, but will be specifically designed for, and promoted to
Switch Either near Suppression Or THOusand – switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/switch-either-near-suppression-or-thousand-switch-to-second-line-versus-who-guided-standard-of-care-for-unsuppressed-patients-on-first-line-art-with-viremia-below-1000-copies/ml-a-multicenter-open-label-randomized-clinical-trial
second-line ART in patients with sustained unsuppressed VL. Methods In this multicenter, parallel-group, open-label, randomized controlled trial conducted in Lesotho, patients on first-line, non-nucleoside reverse
Facilitate the openIMIS team’s participation in the Global Goods Innovators Summit (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/facilitate-the-openimis-teams-participation-in-the-global-goods-innovators-summit
UN Secretary-General, in the Roadmap for Digital Cooperation, as “open source software, open data, open AI models, open standards and open content that adhere to privacy and other applicable laws and best [...] systems. As part of the openIMIS Initiative, Swiss TPH contributes to the platform's development and implementation. In light of this, Swiss TPH submitted the request to include openIMIS in the Global Good
openIMIS:Innovation and learning in social protection (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/openimisinnovation-and-learning-in-social-protection
Under this project, Swiss TPH provides knowledge on openIMIS to improve capacity within (and outside) the openIMIS community to implement openIMIS, improve the quality of the released product and support [...] studies. We enhance the existing openIMIS Implementation starter kit, costing tools, training materials and other resources on the knowledge base of openIMIS (the openIMIS Wiki, website, github repository [...] for identified features from the openIMIS issue queue. We provide core...
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box (Publications)
prevent the emergence of resistance. METHODS: We screened 400 drug-like compounds contained in the open-access Pandemic Response Box (PRB) against newly transformed schistosomula (NTS) at a concentration
Post-exposure lopinavir-ritonavir prophylaxis versus surveillance for individuals exposed to SARS-CoV-2: the COPEP pragmatic open-label, cluster... (Publications)
(LPV/r) was repurposed as a potential PEP agent against COVID-19. Methods: We conducted a pragmatic open-label, parallel, cluster-randomised superiority trial in four sites in Switzerland and Brazil between
Oral fexinidazole for stage 1 or early stage 2 African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a prospective, multicentre, open-label,... (Publications)
the safety and efficacy of fexinidazole in early g-HAT. METHODS: In this prospective, multicentre, open-label, single-arm cohort study, patients with stage 1 or early stage 2 g-HAT were recruited from eight
