Recherche de open.

1. Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label... (Publications)

   Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label randomized trial

   Pertinence:

   point to activity against cestodes and Strongyloides ratti. METHODOLOGY/PRINCIPAL FINDINGS: In an open-label randomized trial, the safety and efficacy of a single oral dose of albendazole or tribendimidine

2. Strikingly decreased community-acquired pneumonia admissions in children despite open schools and day-care facilities in Switzerland (Publications)

   Strikingly decreased community-acquired pneumonia admissions in children despite open schools and day-care facilities in Switzerland

   Pertinence:

3. Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after... (Publications)

   Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after childbirth in Tanzania: a parallelgroup, open-label, randomised controlled phase 3 trial

   Pertinence:

   following childbirth in women with iron deficiency anaemia in Tanzania. Methods: This parallel-group, open-label, randomised controlled phase 3 trial was done at Bagamoyo District Hospital and Mwananyamala

4. Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and... (Publications)

   Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania

   Pertinence:

   an unsuppressed viral load (VL) while taking antiretroviral therapy (ART). METHODS: GIVE MOVE is an open-label randomised clinical trial enrolling children and adolescents (> /=6 months to /=400 copies/mL

5. Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an... (Publications)

   Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an open-label, randomized controlled trial

   Pertinence:

   Background

6. Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized... (Publications)

   Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho

   Pertinence:

   benefit from a switch to second-line treatment. METHODS AND FINDINGS: This multicenter, parallel-group, open-label, superiority, randomized controlled trial enrolled patients on first-line ART containing no

7. Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster... (Publications)

   Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial

   Pertinence:

   INTRODUCTION

8. Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against <em>Schistosoma haematobium</em>: a randomized, exploratory,... (Publications)

   Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against <em>Schistosoma haematobium</em>: a randomized, exploratory, open-label trial

   Pertinence:

   BACKGROUND: Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The an

9. Orally active antischistosomal early leads identified from the open access malaria box (Publications)

   Orally active antischistosomal early leads identified from the open access malaria box

   Pertinence:

   BACKGROUND: Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline t

10. Eleven-year single-center experience with the ATS Open Pivot Bileaflet heart valve (Publications)

    Eleven-year single-center experience with the ATS Open Pivot Bileaflet heart valve

    Pertinence:

    BACKGROUND: The ATS Open Pivot Heart Valve was first introduced in 1992 and has been implanted routinely at our institution since 1993. Valve selection was based on surgeon preference. The objective of [...] 11-year experience demonstrates low rates of adverse events and valve-related complications with the ATS Open Pivot heart valve