Characterization of the Ca2+-gated and voltage-dependent k+-channel slo-1 of nematodes and its interaction with emodepside (Publications)
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics. The mode of action of
How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using mini-FLOTAC? (Publications)
BACKGROUND: Kato-Katz is a widely used method for the diagnosis of soil-transmitted helminth infection. Fecal samples cannot be preserved, and hence, should be processed on the day of collection and e
<em>Plasmodium vivax</em> populations are more genetically diverse and less structured than sympatric <em>Plasmodium falciparum</em> populations (Publications)
INTRODUCTION: The human malaria parasite, Plasmodium vivax, is proving more difficult to control and eliminate than Plasmodium falciparum in areas of co-transmission. Comparisons of the genetic struct
Can smartphones and tablets improve the management of childhood illness in Tanzania? A qualitative study from a primary health care worker's... (Publications)
BACKGROUND: The impact of the Integrated Management of Childhood Illness (IMCI) strategy has been less than anticipated because of poor uptake. Electronic algorithms have the potential to improve qual
Costing the supply chain for delivery of ACT and RDTs in the public sector in Benin and Kenya (Publications)
BackgroundStudies have shown that supply chain costs are a significant proportion of total programme costs. Nevertheless, the costs of delivering specific products are poorly understood and ballpark e
Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet... (Publications)
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the s