Combination chemotherapy against <em>Clonorchis sinensis</em>: experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in the... (Publications)
Caused by the Chinese liver fluke Clonorchis sinensis, clonorchiasis is of growing public health importance. Treatment and control of the disease relies on a single drug - praziquantel - and little in
Safety, tolerability and immunogenicity of new formulations of the <em>Plasmodium falciparum </em>malaria peptide SPf66 combined with the... (Publications)
SPf66 is a synthetic malaria peptide vaccine, which has been widely tested in combination with aluminium hydroxide (alum) as the adjuvant. Since this formulation is weakly immunogenic, we sought to im
Anaerobic performance in 5- to 7-yr-old children of low birthweight (Publications)
PURPOSE: This study was intended to determine whether anaerobic muscle performance is deficient in 5- to 7-yr-old children of extremely low birthweight (ELBW, 500-999 g) and very low birthweight (VLBW
Clonorchicidal properties of the synthetic trioxolane OZ78 (Publications)
Because the synthetic trioxolane OZ78 is active against the liver fluke Fasciola hepatica, we were motivated to investigate the in vivo and in vitro activity against another liver fluke, namely Clonor
Activity of artemether and OZ78 against triclabendazole-resistant <em>Fasciola hepatica</em> (Publications)
Triclabendazole is the drug of choice against Fasciola hepatica infections in humans and animals. However, parasite resistance against triclabendazole is spreading in the veterinary field, and there a
Acridine Orange for malaria diagnosis: its diagnostic performance, its promotion and implementation in Tanzania, and the implications for malaria... (Publications)
One hundred years ago, Giemsa's stain was employed for the first time for malaria diagnosis. Giemsa staining continues to be the method of choice in most malarious countries, although, in the recent p
Beijing sublineages of <em>Mycobacterium tuberculosis</em> differ in pathogenicity in the Guinea pig (Publications)
The Beijing family of Mycobacterium tuberculosis strains is part of lineage 2 (also known as the East Asian lineage). In clinical studies, we have observed that isolates from the sublineage RD207 of l
Quality of primary outpatient services in Dar-es-Salaam: a comparison of government and voluntary providers (Publications)
This study aimed to test whether voluntary agencies provide care of better quality than that provided by government with respect to primary curative outpatient services in Dar-es-Salaam. All non-gover
