Inhibitors of adenosine consuming parasites through polymer-assisted solution phase synthesis of lipophilic 5'-amido-5'-deoxyadenosine... (Publications)
Given the more or less global spread of multidrug-resistant plasmodia, structurally diverse starting points for the development of chemotherapeutic agents for the treatment of malaria are urgently nee
Effect of environmental tobacco smoke exposure on respiratory symptoms in children (Publications)
AIMS: This study determines the prevalence of exposure to environmental tobacco smoke and its relation to respiratory and allergic symptoms among schoolchildren in Switzerland. METHODS: We studied 447
Comparison of analytical methods for the evaluation of antibody responses against epitopes of polymorphic protein antigens (Publications)
Surface exposed protein antigens of the malaria parasite Plasmodium falciparum frequently harbor multiple dimorphic amino acid positions. These are associated with parasite immune evasion and represen
Survey on the occurrence of Brachyspira species and Lawsonia intracellularis in children living on pig farms (Publications)
The occurrence of Brachyspira species and Lawsonia intracellularis was investigated by PCR analyses of faeces from 60 children living on European pig farms. In addition, 60 other children were include
Anti-trypanosomal activity of Fexinidazole: a new oral nitroimidazole drug candidate for the treatment of sleeping sickness (Publications)
Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis (HAT)) caused by infection with species of the pro
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)
The Plasmodium falciparum merozoite surface protein-1 19 kDa fragment (MSP-1(19)) comprises two closely packed EGF-like domains (EGF=epidermal growth factor), each stabilized by three disulfide bonds.
Prognostic value of stress testing in patients over 75 years of age with chronic angina (Publications)
STUDY OBJECTIVES: To define the prognostic value of stress testing (STRT) in patients > or= 75 years of age. DESIGN: Multicenter prospective randomized trial. SETTING: Tertiary care centers. PATIENTS:
Health system costs of menstrual regulation and care for abortion complications in Bangladesh (Publications)
CONTEXT: Treatment of complications of unsafe abortion can be a significant financial drain on health system resources, particularly in developing countries. In Bangladesh, menstrual regulation is pro
Blood-stage parasitaemia and age determine <em>Plasmodium falciparum</em> and <em>P. vivax</em> gametocytaemia in Papua New Guinea (Publications)
A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083 samples were collected in a cross-sectional
