A potent and selective reaction hijacking inhibitor of <em>Plasmodium falciparum</em> tyrosine tRNA synthetase exhibits single dose oral efficacy... (Publications)
The Plasmodium falciparum cytoplasmic tyrosine tRNA synthetase (PfTyrRS) is an attractive drug target that is susceptible to reaction-hijacking by AMP-mimicking nucleoside sulfamates. We previously id
Click coupling of flavylium dyes with plasmodione analogues: towards new redox-sensitive pro-fluorophores (Publications)
The development of redox-sensitive molecular fluorescent probes for the detection of redox changes in Plasmodium falciparum-parasitized red blood cells remains of interest due to the limitations of cu
Noise causes cardiovascular disease: it's time to act (Publications)
BACKGROUND: Chronic transportation noise is an environmental stressor affecting a substantial portion of the population. The World Health Organization (WHO) and various studies have established associ
Applied body-fluid analysis by wearable devices (Publications)
Wearable sensors are a recent paradigm in healthcare, enabling continuous, decentralized, and non- or minimally invasive monitoring of health and disease. Continuous measurements yield information-ric
Burden of disease scenarios by state in the USA, 2022-50: a forecasting analysis for the Global Burden of Disease Study 2021 (Publications)
BACKGROUND: The capacity to anticipate future health issues is important for both policy makers and practitioners in the USA, as such insights can facilitate effective planning, investment, and implem
Synthesis of 1,2,3-triazole-methyl-menadione derivatives: evaluation of electrochemical and antiparasitic properties against two blood-dwelling... (Publications)
This study explores the synthesis and evaluation of novel 1,2,3-triazole-methyl-1,4-naphthoquinone hybrids, focusing on their electrochemical properties and antiparasitic efficacies against two human
Conditional and unconditional social transfers, early-life nutrition, and child growth: a randomized clinical trial (Publications)
IMPORTANCE: Rates of exclusive breastfeeding are declining despite the numerous benefits to mothers and their children. OBJECTIVE: To assess the effectiveness of conditional and unconditional social t
Systems modelling and simulation to guide targeted investments to reduce youth suicide and mental health problems in a low-middle-income country (Publications)
BACKGROUND: Despite suicide's public health significance and global mental health awareness, current suicide prevention efforts show limited impact, posing a challenge for low- and middle-income count
