Tambjamines as fast-acting multistage antimalarials (Publications)
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover and develop. Herein, we report results for natural product-i
One-year impact of behavioural interventions on schistosomiasis-related knowledge, attitude and practices of primary schoolchildren in Pemba, Tanzania (Publications)
BACKGROUND: Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are goals set by the World Health Organization for 2030. Behaviour change commu
Ambient air pollution exposure and incidence of cataract surgery: the prospective 3City-Alienor study (Publications)
PURPOSE: Cataract, the leading cause of blindness worldwide, is a multifactorial disease involving oxidative stress mechanisms. The aim of our study was to investigate the relationship between air pol
Meteorological factors, population immunity, and COVID-19 incidence: a global multi-city analysis (Publications)
OBJECTIVES: While COVID-19 continues to challenge the world, meteorological variables are thought to impact COVID-19 transmission. Previous studies showed evidence of negative associations between hig
Praziquantel and factor H recruitment differentially affect the susceptibility of <em>Schistosoma manson</em>i to complement-mediated damage (Publications)
BACKGROUND: Schistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a k
Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of <em>Trichuris trichiura</em>... (Publications)
Trichuris trichiura, a soil-transmitted helminth (STH), often persists after a single dose of anthelminthic treatment. To overcome limited efficacy against T. trichiura of benzimidazoles (albendazole
Air pollution mixture complexity and its effect on PM2.5-related mortality: a multicountry time-series study in 264 cities (Publications)
BACKGROUND: Fine particulate matter (PM(2.5)) occurs within a mixture of other pollutant gases that interact and impact its composition and toxicity. To characterize the local toxicity of PM(2.5), it
Whole genome sequencing of <em>M. tuberculosis</em> for disease control in high-burden settings: study protocol for a cluster randomized controlled... (Publications)
BACKGROUND: Retrospective and descriptive molecular epidemiology studies have shown that Mycobacterium tuberculosis whole genome sequencing can identify outbreaks and disease transmission events with
