The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity (Publications)
Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TL
Towards host-directed therapies for tuberculosis [Comment] (Publications)
The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjun
Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural... (Publications)
BACKGROUND: Early-life exposure to environmental microbial agents may be associated with development of wheezing and allergic diseases. OBJECTIVE: To assess the association of microbial exposure in ru
<em>Schistosoma mansoni</em> antigen detects <em>Schistosoma mekongi</em> infection (Publications)
Northern Cambodia and Southern Laos are highly endemic for Schistosoma mekongi. However, there is currently no immunological assay available that is specific for this form of schistosomiasis. We have
Eco-social determinants of <em>Schistosoma japonicum</em> infection supported by multi-level modelling in Eryuan county, People's Republic of... (Publications)
Schistosomiasis remains of considerable public health concern in many tropical and subtropical regions of the world, including the People's Republic of China. The effectiveness of schistosomiasis cont
Phosphorylation of the ribosomal protein S6, a marker of mTOR pathway activation, is strongly increased in hypertrophic scars and keloids [Research... (Publications)
Hypertrophic scars and keloids are fibrous overgrowths, which may develop in response to skin injury, but spontaneous forms also exist. It has been reported that tissue extracts from keloids contain e
Consumption of unprocessed cow's milk protects infants from common respiratory infections (Publications)
BACKGROUND: Breast-feeding is protective against respiratory infections in early life. Given the co-evolutionary adaptations of humans and cattle, bovine milk might exert similar anti-infective effect
Repeated stool sampling and use of multiple techniques enhance the sensitivity of helminth diagnosis: a cross-sectional survey in southern Lao... (Publications)
Intestinal parasitic infections are common in Lao People's Democratic Republic (Lao PDR). We investigated the accuracy of the Kato-Katz (KK) technique in relation to varying stool sampling efforts, an
