Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability (Publications)
Four new compounds, the monomeric dioncotetralones A (6 a) and B (6 b) and the dimeric compounds jozimine A3 (7) and jozimine A4 (9), were semi-synthesized from the natural product dioncophylline A (4
Acquired resistance to bedaquiline and delamanid in therapy for tuberculosis (Publications)
Treatment of multidrug-resistant Mycobacterium tuberculosis is a challenge. This letter describes the emergence of resistance to new therapies, bedaquiline and delamanid.
Health impacts of anthropogenic biomass burning in the developed world (Publications)
Climate change policies have stimulated a shift towards renewable energy sources such as biomass. The economic crisis of 2008 has also increased the practice of household biomass burning as it is ofte
Discovery of inhibitors of<em> Trypanosoma brucei</em> by phenotypic screening of a focused protein kinase library (Publications)
A screen of a focused kinase inhibitor library against Trypanosoma brucei rhodesiense led to the identification of seven series, totaling 121 compounds, which showed > 50 % inhibition at 5 muM. Screen
Still far from 90-90-90: virologic outcomes of children on antiretroviral therapy in nurse-led clinics in rural Lesotho (Publications)
This survey assessed virologic outcomes of children on antiretroviral therapy and potential predictors in 10 nurse-led clinics in Lesotho. Success was achieved in 72% of the 191 children. No predictor
Matching comprehensive health insurance reimbursements to their real costs: the case of antenatal care visits in a region of Peru (Publications)
BACKGROUND: Prepaid contributory systems are increasingly being recognized as key mechanisms in achieving universal health coverage in low and middle-income countries. Peru created the Seguro Integral
