Antiprotozoal effect of <em>Artemisia indica</em> extracts and essential oil (Publications)
Diverse solvent extracts of Artemisia indica leaves originating from the West Bengal region (India) were assessed for the content of artemisinin and characteristic Artemisia polymethoxyflavonoids, nam
Changing from whole-cell to acellular pertussis vaccines would trade superior tolerability for inferior protection (Publications)
Notifications of infant deaths, assumed to be related to the introduction of new pentavalent DTwP-Hib-HBV childhood vaccines, caused, during 2008-2010 in few Asian countries, temporary interruptions o
Costing RTS,S introduction in Burkina Faso, Ghana, Kenya, Senegal, Tanzania, and Uganda: a generalizable approach drawing on publicly available data (Publications)
Recent results from the phase 3 trial of RTS,S/AS01 malaria vaccine show that the vaccine induced partial protection against clinical malaria in infants and children; given the high burden of the dise
No fever, no malaria? A diagnostic challenge in an immunocompromised patient (Publications)
We describe the case of an immunosuppressed women with proven malaria tropicana. Fever was not reported with this patient. We conclude that the concept of using fever as a primary surrogate indicator
Meta-analysis identifies seven susceptibility loci involved in the atopic march (Publications)
Eczema often precedes the development of asthma in a disease course called the 'atopic march'. To unravel the genes underlying this characteristic pattern of allergic disease, we conduct a multi-stage
6-Arylpyrazine-2-carboxamides: a new core for <em>Trypanosoma brucei</em> inhibitors (Publications)
From a whole-organism high throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei, we recently identified eight new unique compounds for the treatment of human African t
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)
OBJECTIVE: We conducted a community survey to estimate the prevalence and describe the features, risk factors, and consequences of convulsive status epilepticus (CSE) among people with active convulsi
The elderly, the young and the pregnant traveler - a retrospective data analysis from a large Swiss Travel Center with a special focus on malaria... (Publications)
BACKGROUND: Vulnerable individuals such as elderly, children/adolescents and pregnant/breastfeeding women increasingly travel overseas. We describe the travel and vaccination patterns of these groups
Pharmacological effects of primaquine ureas and semicarbazides on the CNS in mice and antimalarial activity in vitro (Publications)
New primaquine (PQ) urea and semicarbazide derivatives 1-4 were screened for the first time for CNS and antimalarial activity. Behavioural tests were performed on mice. In vitro cytotoxicity on L-6 ce
