Effects of hygiene and defecation behavior on helminths and intestinal protozoa infections in Taabo, Côte d'Ivoire (Publications)
BACKGROUND: More than 1 billion people are currently infected with soil-transmitted helminths and schistosomes. The global strategy to control helminthiases is the regular administration of anthelmint
Development of an<em> in vitro</em> drug sensitivity assay based on newly excysted larvae of <em>Echinostoma caproni</em> (Publications)
BACKGROUND: Echinostomiasis is one of the major food-borne trematodiases and the species Echinostoma caproni serves as a useful model for trematocidal drug discovery. The current in vitro drug sensiti
Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers (Publications)
INTRODUCTION: With the renewed drive towards malaria elimination, there is a need for improved surveillance tools. While time series analysis is an important tool for surveillance, prediction and for
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in<em> Plasmodium falciparum</em> protein export (Publications)
Malaria blood stage parasites export a large number of proteins into their host erythrocyte to change it from a container of predominantly hemoglobin optimized for the transport of oxygen into a niche
Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis (Publications)
There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus re
