Trypanosomes have divergent kinesin-2 proteins that function differentially in flagellum biosynthesis and cell viability (Publications)
Trypanosoma brucei, the causative agent of African sleeping sickness, has a flagellum that is crucial for motility, pathogenicity, and viability. In most eukaryotes, the intraflagellar transport (IFT)
Communities and clinical trials: a case study from the RTS,S malaria vaccine trials in eastern Africa (Publications)
When clinical trials enter human communities, two complex systems merge-creating challenges for the clinical trial team and the local human community. This is of particular relevance for clinical tria
Mobile pastoralists in Africa: a blind spot in global health surveillance (Publications)
Mobile pastoralists subsist primarily on herds of livestock such as camels, cattle, and goats, migrating seasonally to access water and grazing areas. Speculative estimates of their global population
Geographical patterns and predictors of malaria risk in Zambia: Bayesian geostatistical modelling of the 2006 Zambia national malaria indicator survey... (Publications)
BACKGROUND: The Zambia Malaria Indicator Survey (ZMIS) of 2006 was the first nation-wide malaria survey, which combined parasitological data with other malaria indicators such as net use, indoor resid
Risk of latent tuberculosis infection in children living in households with tuberculosis patients: a cross sectional survey in remote northern Lao... (Publications)
ABSTRACT: BACKGROUND: Tuberculosis is highly prevalent in Laos (289 per 100,000). We evaluated the risk of latent tuberculosis infection (LTBI) among children (0-15 years) living with tuberculosis pat
A large cross-sectional community-based study of newborn care practices in southern Tanzania (Publications)
Despite recent improvements in child survival in sub-Saharan Africa, neonatal mortality rates remain largely unchanged. This study aimed to determine the frequency of delivery and newborn-care practic
Three different <em>Plasmodium</em> species show similar patterns of clinical tolerance of malaria infection (Publications)
BACKGROUND: In areas where malaria endemicity is high, many people harbour blood stage parasites without acute febrile illness, complicating the estimation of disease burden from infection data. For P
Estimating the numbers of malaria infections in blood samples using high-resolution genotyping data (Publications)
People living in endemic areas often habour several malaria infections at once. High-resolution genotyping can distinguish between infections by detecting the presence of different alleles at a polymo
Costs and effects of the Tanzanian national voucher scheme for insecticide-treated nets (Publications)
BACKGROUND:The cost-effectiveness of insecticide-treated nets (ITNs) in reducing morbidity and mortality is well established. International focus has now moved on to how best to scale up coverage and
