Experience and challenges from clinical trials with malaria vaccines in Africa (Publications)
Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense
Reduced risk of <em>Plasmodium vivax</em> malaria in Papua New Guinean children with Southeast Asian ovalocytosis in two cohorts and a case-control... (Publications)
BACKGROUND: The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Delta27) protects against cerebral malari
Malaria knowledge and long-lasting insecticidal net use in rural communities of central Côte d'Ivoire (Publications)
BACKGROUND: To improve effectiveness of malaria control interventions, it is essential to deepen the knowledge of contextual factors that govern people's practice for preventive and curative measures.
Effect of schistosomiasis and soil-transmitted helminth infections on physical fitness of school children in Côte d'Ivoire (Publications)
BACKGROUND: Schistosomiasis and soil-transmitted helminthiasis are important public health problems in sub-Saharan Africa causing malnutrition, anemia, and retardation of physical and cognitive develo
High sensitivity detection of <em>Plasmodium</em> species reveals positive correlations between infections of different species, shifts in age... (Publications)
BACKGROUND: When diagnosed by standard light microscopy (LM), malaria prevalence can vary significantly between sites, even at local scale, and mixed species infections are consistently less common th
Spatially-explicit risk profiling of<em> Plasmodium falciparum</em> infections at a small scale: a geostatistical modelling approach (Publications)
BACKGROUND: There is a renewed political will and financial support to eradicate malaria. Spatially-explicit risk profiling will play an important role in this endeavour. Patterns of Plasmodium falcip
Ensemble modeling of the likely public health impact of a pre-erythrocytic malaria vaccine (Publications)
BACKGROUND: The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (
MER41 repeat sequences contain inducible STAT1 binding sites (Publications)
Chromatin immunoprecipitation combined with massively parallel sequencing methods (ChIP-seq) is becoming the standard approach to study interactions of transcription factors (TF) with genomic sequence