Toll-like receptor 2 as a major gene for asthma in children of European farmers (Publications)
BACKGROUND: The finding that the prevalence of asthma and allergies is less frequent in children raised on animal farms has led to the conjecture that exposure to microbial products modifies immune re
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis (Publications)
PURPOSE OF REVIEW: Praziquantel (PZQ) is the only drug being used to treat human schistosomiasis on a large scale. This review focuses on current knowledge about the mechanisms of action of PZQ, prosp
Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement (Publications)
BACKGROUND: The question of whether air pollution contributes to asthma onset remains unresolved. OBJECTIVES: In this study, we assessed the association between asthma onset in children and traffic-re
Exploring prospects of novel drugs for tuberculosis (Publications)
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However,
Antitrypanosomal sesquiterpene lactones from <em>Saussurea costus</em> (Publications)
In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense. Subsequent HPLC
