Liver morbidity due to <em>Schistosoma mekongi</em> in Cambodia after seven rounds of mass drug administration (Publications)
Severe liver disease due to Schistosoma mekongi was frequent in northern Cambodia. Between 1995 and 2002, seven rounds of mass chemotherapy (praziquantel) reduced infection from 50% to below 3%. In 20
Tuberculosis control in refugee populations: a challenge to both relief agencies and national programs (Publications)
Today's worldwide tuberculosis epidemic and the movement of a growing number of refugees overlap geographically and have made tuberculosis control in refugee populations an issue of increasing importa
Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with <em>Fasciola hepatica</em> (Publications)
OBJECTIVES: The pharmacokinetic (PK) parameters of artesunate, recently discovered to possess promising trematocidal activity, and its main metabolite dihydroartemisinin (DHA) were determined in rats
Activity of antiandrogens against juvenile and adult <em>Schistosoma mansoni </em>in mice (Publications)
Objectives The antischistosomal properties of the marketed antiandrogens bicalutamide, flutamide, nilutamide and cyproterone acetate were studied both in vivo and in vitro. Methods Schistosoma mansoni
Food-borne trematodiasis: current chemotherapy and advances with artemisinins and synthetic trioxolanes (Publications)
Over 40 million people are infected with food-borne trematodes and 750 million are at risk of food-borne trematodiasis, and yet this tropical disease is neglected. The current arsenal for the treatmen
Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation (Publications)
We present a novel application of the heteronuclear statistical total correlation spectroscopy (HET-STOCSY) approach utilizing statistical correlation between one-dimensional 19F/1H NMR spectroscopic
