Ultrastructural alterations in adult <em>Schistosoma mansoni</em> caused by artemether (Publications)
Progress has been made over the last decade with the development and clinical use of artemether as an agent against major human schistosome parasites. The tegument has been identified as a key target
Identification of fecal input sites in spring water by selection and genotyping of multiresistant <em>Escherichia coli</em> (Publications)
The localization of fecal input sites is important for water quality management. For this purpose, we have developed a new approach based on a three-step procedure, including a preparatory phase, the
Potential long-term toxicity of repeated orally administered doses of artemether in rats (Publications)
Artemether, an efficacious antimalarial drug, effectively prevents patent schistosome infections and morbidity, as established in laboratory models and in clinical trials. In view of concern about the
Assessing health impacts in complex eco-epidemiological settings in the humid tropics: advancing tools and methods (Publications)
In the developing world. large-scale projects in the extractive industry and natural resources sectors are often controversial and associated with long-term adverse health consequences to local commun
Novel <em>Bacteroides</em> host strains for detection of human- and animal-specific bacteriophages in water (Publications)
Bacteriophages active against specific Bacteroides host strains were shown to be suitable for detection of human faecal pollution. However, the practical application of this finding is limited because
Imidazolopiperazines: hit to lead optimization of new antimalarial agents (Publications)
Starting from a hit series from a GNF compound library collection and based on a cell-based proliferation assay of Plasmodium falciparum, a novel imidazolopiperazine scaffold was optimized. SAR for th
